Capillaritis associated with interferon-alfa treatment of chronic hepatitis C infection - 13/06/12
Abstract |
We report the case of a 36-year-old man who was referred with an asymptomatic eruption that started on both lower legs. This started shortly after being commenced on interferon-alfa for chronic hepatitis secondary to hepatitis C. Clinically, the eruption was consistent with a capillaritis (pigmented purpuric dermatosis). Histology confirmed this to be lymphocytic vasculitis. Lymphocytic vasculitis is frequently identified in the salivary glands of patients who are hepatitis C positive. Although leukocytoclastic vasculitis confined to the skin is frequently reported with hepatitis C, lymphocytic vasculitis is rarely reported. We consider that the lymphocytic vasculitis in our patient occurred as a result of interferon-alfa treatment because of the strong temporal relationship between the onset of the skin eruption and drug therapy. (J Am Acad Dermatol 2000;43:937-8.)
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 | This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology. |
| Reprint requests: Dr Girish Gupta, Department of Dermatology, Western Infirmary, Dumbarton Road, Glasgow, G11 6NT, United Kingdom. |
 | J Am Acad Dermatol 2000;43:937-8. |
Vol 43 - N° 5P2
P. 937-938 - novembre 2000 Retour au numéro
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