Human papillomavirus–related genital disease in the immunocompromised host : Part I - 13/05/12
Abstract |
Human papillomavirus (HPV) is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. These conditions are of particular concern in immunocompromised individuals who have higher risk of malignant transformation and are more difficult to treat. This is part I of a two-part review that will highlight the cutaneous features of condyloma acuminata and vaginal, vulvar, penile, and anal intraepithelial neoplasias, with an emphasis on presentation of these HPV-mediated diseases in the immunocompromised host. Counseling patients about these conditions requires a thorough understanding of the epidemiology, natural history of HPV, transmission and infectivity, risk of malignancy, and the role of the host immune response in clearing HPV lesions. Part II will provide an updated review of available treatments, with a focus on recent advances and the challenges faced in successfully treating HPV lesions in immunocompromised patients.
Le texte complet de cet article est disponible en PDF.Key words : AIDS, anal intraepithelial neoplasia, Buschke–Lowenstein tumor, condyloma acuminata, HIV, human papillomavirus, organ transplant, penile intraepithelial neoplasia, vulvar intraepithelial neoplasia
Abbreviations used : AIN, BLT, CA, DRE, HAART, HPV, MSM, PIN, VIN
Plan
Funding sources: None. |
Vol 66 - N° 6
P. 867.e1-867.e14 - juin 2012 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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