Necrotic cutaneous lesions induced by hypereosinophilic syndrome secondary to a T-cell lymphoma - 11/05/12
Abstract |
Cutaneous lesions of hypereosinophilic syndrome (HES) may display various presentations. These are important to recognize to allow early diagnosis. We report an unusual case of a young man with HES secondary to a splenic T-cell lymphoma, revealed by diffuse necrotic cutaneous lesions. Later on, brain and heart infarctions developed, leading to the patient's death. Analysis of skin biopsy specimens showed occluded dermal vessels surrounded by activated eosinophils. Because a complete analysis of hemostasis was unremarkable, these findings suggest that dermal vessel thrombosis was the direct consequence of the migration of activated eosinophils. Cutaneous lesions of HES are protean and probably reflect the differences between the lesional events induced in situ by activated eosinophils. (J Am Acad Dermatol 2001;46:S133-6.)
Le texte complet de cet article est disponible en PDF.Plan
 | This supplement is made possible through an unrestricted grant from Stiefel Laboratories to the American Academy of Dermatology. |
| Supported in part by Université Paris VII and ARC subvention libre 9052. |
 | Reprint requests: Sélim Aractingi, MD, Unité de Dermatologie, Hôpital Tenon, 4, rue de la Chine, 75020, Paris, France. E-mail: selim.aractingi@tnn.ap-hop-paris.fr. |
Vol 46 - N° 5S
P. S133-S136 - mai 2002 Retour au numéro
Article précédent
- Multifocal disseminated lipoatrophy secondary to intravenous corticosteroid administration in a patient with adrenal insufficiency
- Jürgen Bauerschmitz, Konrad Bork
- Bullous adult T-cell lymphoma/leukemia and human T-cell lymphotropic virus-1 associated myelopathy in a 60-year-old man
- Elias J. Michael, Joseph J. Shaffer, Henry E. Collins, Marc E. Grossman
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?