Community-onset healthcare-related urinary tract infections: Comparison with community and hospital-acquired urinary tract infections - 18/04/12
Summary |
Objectives |
To analyze the characteristics of infection, adequacy of empirical treatment and outcome of patients with community-onset healthcare-associated (HCA) urinary tract infections (UTI) and compare them with hospital (HA) and community-acquired (CA) UTI.
Methods |
Prospective observational cohort study performed at a university 600-bed hospital between July 2009 and February 2010. Patients with UTI requiring hospital admission were included. Epidemiological, clinical and outcome data were recorded.
Results |
251 patients were included. Patients with community-onset HCA UTI were older, had more co-morbidities and had received previous antimicrobial treatment more frequently than CA UTI (p = 0.02, p = 0.01 and p < 0.01). ESBL-Escherichia coli and Pseudomonas aeruginosa infections were more frequent in HCA than in CA UTI (p = 0.03 and p < 0.01). Inadequate empirical treatment was not significantly different between community-onset HCA and CA. Factors related to mortality were P. aeruginosa infection (OR 6.51; 95%CI: 1.01–41.73), diabetes mellitus (OR 22.66; 95%CI: 3.61–142.21), solid neoplasia (OR 22.48; 95%CI: 3.38–149.49) and age (OR 1.15; 95%CI 1.03–1.28).
Conclusions |
Epidemiological, clinical and microbiological features suggest that community-onset HCA UTI is different from CA and similar to HA UTI. However, in our series inadequate empirical antimicrobial therapy and mortality were not significantly higher in community-onset HCA than in CA UTI.
Le texte complet de cet article est disponible en PDF.Keywords : Urinary tract infection, Healthcare-associated infections, Antimicrobial resistance
Plan
Vol 64 - N° 5
P. 478-483 - mai 2012 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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