Have French recommendations had an impact on the treatment and survival of middle and lower rectal cancer patients? - 20/03/12
, Andreas Kubo b, Claire Philippe b, Jean-Marc Bigourdan b, Claudine Gras-Aygon a, Brigitte Tretarre a
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Summary |
Objective |
Compare the survival of middle and lower rectal cancer (MLRC) patients before and after the 1994 issue of rectal cancer (RC) consensus conference recommendations.
Methods |
Cases of MLRC noted in the Hérault department of France in 1992 (n=58) and 2000 (n=93) yielded exhaustive epidemiological, clinical-pathological and treatment data that were used to compare MLRC patient management and survival in these two periods.
Results |
Significantly more lymph nodes (≥8) were harvested in 2000 (≥8, 47%) than in 1992. In all, 45 patients (77.6%) received radiotherapy in 1992, and 74 (82%) in 2000. Chemotherapy was employed in 15 patients (25.9%) in 1992 and in 39 patients (43%) in 2000. Chemotherapy and radiotherapy, together with sphincter conservation, were dependent upon the year. Overall 5-year relative survival for rectal cancer in the Hérault department did not vary between 1992 (56%) and 2000 (56%). Independent poor prognostic factors were the same in both years: age over 75years, lymph node involvement and metastases. Management place and year had no significant impact on prognosis.
Conclusion |
The recommendations made have had little impact on disease management and the quality of anatomic pathology reports, and have not improved 5-year relative survival.
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Vol 36 - N° 2
P. 156-161 - avril 2012 Retour au numéro
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