On the pathogenesis of post primary tuberculosis: The role of bronchial obstruction in the pathogenesis of cavities - 27/12/11
Tel.: +1 713 500 5301; fax: +1 713 500 0732.Summary |
Mycobacterium tuberculosis produces two distinct types of disease: primary and post primary tuberculosis. We recently reported that post primary tuberculosis begins in immunocompetent adults as an endogenous lipid pneumonia that abruptly undergoes necrosis to produce cavities. Obstruction of bronchi by endobronchial tuberculosis is a consistent finding in developing post primary tuberculosis. This paper reports a case of obstructive pneumonia caused by cancer that underwent rapid necrosis to produce a cavity that was similar to those produce by tuberculosis. Analysis of this case with the relevant literature supports the hypothesis that bronchial obstruction is an essential contributor to the development of post primary tuberculosis and that it may help explain the localized suppression of host defense mechanisms in adult pulmonary tuberculosis.
Le texte complet de cet article est disponible en PDF.Keywords : Post primary tuberculosis, Lung, Pathology, Cavity, Cancer, Malignancy
Plan
 | Presented at: Texas Tuberculosis Research Symposium, Galveston, TX, April 11, 2011. Submitted for publication in proceedings of the symposium as a special issue of the journal Tuberculosis. |
Vol 91 - N° S1
P. S6-S10 - décembre 2011 Retour au numéro
Article précédent
- Tuberculosis in Texas 2011 – Victories and challenges
- Lisa Armitige, Charles Wallace
- A current review of infection control for childhood tuberculosis
- Andrea T. Cruz, Jeffrey R. Starke
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?