Bone mineral density assessed by dual-energy X-ray absorptiometry in patients with viral or alcoholic compensated cirrhosis. A prospective study - 06/12/11
, J. Reboul-Marty c , G. Chalès d , Y. Lalatonne e , V. Bourcier a , V. Grando a , N. Barget a , M. Beaugrand a , J.-C. Trinchet a , N. Ganne-Carrié a, ⁎ 
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Summary |
Background/aim |
Cirrhosis is considered as a risk factor for osteoporosis whose prevalence is poorly known. The aim was to assess prospectively bone mineral density (BMD) in patients with alcoholic or viral compensated cirrhosis.
Methods |
From 2006 to 2008, patients with viral or alcoholic compensated cirrhosis had BMD assessment by dual-energy X-ray absorptiometry. The prevalence of osteopenia (−2.5SD<T-score<−1SD) and osteoporosis (T-score≤−2.5SD), and the influence of age, gender and aetiology of cirrhosis were assessed using univariate and multiple regression analysis.
Results |
One hundred and nine patients were studied (72 men, 55.3±11.4 years and 37 women, 65.2±11.0); with HBV (n=35), HCV (n=43), or alcoholic cirrhosis (n=31). At the lumbar spine, 25 patients had osteopenia and 12 had osteoporosis. At the femoral site, 23 had osteopenia and 4 had osteoporosis. Female gender had an independent decreased effect on the total BMD.
Conclusions |
The prevalence of osteoporosis was up to 11% at the lumbar spine, greater in women independently of age, without significant difference according to the aetiology of cirrhosis.
Le texte complet de cet article est disponible en PDF.Abbreviations : BMD, DXA, WHO, HCV, HBV, SD
Plan
Vol 35 - N° 11
P. 731-737 - novembre 2011 Retour au numéro
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