Detection of prognostic factors for oral allergy syndrome in patients with birch pollen hypersensitivity - 11/09/11
Abstract |
To determine why a significant proportion of birch pollen–sensitive patients do not have the oral allergy syndrome (OAS), possible predictive in vivo or in vitro tests for OAS were sought in a large retrospective and prospective follow-up study performed in 283 patients with clinical evidence of birch pollen hypersensitivity. OAS was associated with more severe respiratory symptoms and with higher birch-specific and total IgE levels; moreover, its onset was clearly related to duration of birch pollinosis. The prospective part of this study, performed in 63 patients without OAS, confirmed these findings and highlighted the very high negative predictive value of both skin prick tests with fresh foods and RAST with food allergens. This work suggests that about 15% of patients with birch pollen hypersensitivity are not prone to OAS and that their anti-birch IgE might be directed against determinants that do not cross-react with food allergens. (J ALLERGY CLIN IMMUNOL 1996;97:611-6.)
Le texte complet de cet article est disponible en PDF.Keywords : oral allergy syndrome, food allergy, birch pollen allergy, skin prick tests
Abbreviations : AU:, BPA:, NPV:, OAS:, PPV:, SPT:
Plan
![]() | From Ambulatorio di Allergologia, Ospedale Caduti Bollatesi, Bollate, Milano, Italia. |
![]() ![]() | Reprint requests: Riccardo Asero, MD, Ambulatorio di Allergologia, Ospedale Caduti Bollatesi, Via Piave 20, 20021 Bollate (MI), Italia. |
![]() | 0091-6749/96 $5.00 + 0 1/1/65923 |
Vol 97 - N° 2
P. 611-616 - février 1996 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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