An ulcerated lesion at the BCG vaccination site during the course of Kawasaki disease - 11/09/11
Abstract |
We describe a bacillus Calmette-Guérin (BCG) granuloma that occurred during the course of Kawasaki disease. A 12-month-old male infant with Kawasaki disease had an erythem-atous indurated plaque with prominent necrotic ulceration at the BCG vaccination site on the left upper arm. Histologic study showed a granulomatous reaction consisting of epithelioid histiocytes, lymphoid cells, and Langhans-type giant cells. No evidence of mycobacterial infection was obtained. The lesion healed completely within 2 weeks without administration of antituberculous agents. We believe that the granulomatous reaction occurred as a result of hypersensitivity to proteins in the BCG vaccine, which appeared after the onset of Kawasaki disease. (J Am Acad Dermatol 1997;37:303-4.)
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 | Reprint requests: Shuichi Kuniyuki, Division of Dermatology, Juso Municipal Hospital, Juso-Higashi 2-3-7, Yodogawa-ku 532, Osaka, Japan. |
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Vol 37 - N° 2S
P. 303-304 - août 1997 Retour au numéro
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