Cutaneous and neurologic disease associated with HTLV-I infection - 11/09/11
From the Dermatology Clinic, University of Wisconsin Hospital and Clinics, Madison,a the Department of Dermatology, Wayne State University School of Medicine, Detroit,b and the Department of Dermatology, New York University, New York.c
Abstract |
Human T-lymphotropic virus type I (HTLV-I) is the etiologic agent of HTLV-I associated myelopathy (HAM)/tropical spastic paresis (TSP), and adult T-cell leukemia/lymphoma (ATLL). ATLL has been associated with HTLV-I in the southeastern United States. However, to our knowledge, no case reports of HAM/TSP in association with ATLL occurring in the United States have been described. We describe a 40-year-old black woman with a 10-year history of recalcitrant psoriasiform eruption and erythrodermic flares. Medical history is additionally significant for a 2-year history of HTLV-I–associated myelopathy and lower extremity spastic paresis. Polymerase chain reaction with Southern blot analysis was used to detect HTLV-I proviral genome from frozen skin biopsy specimens and peripheral blood mononuclear cells. (J Am Acad Dermatol 1997;36:869-71.)
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This article is made possible through an educational grant from the Dermatological Division, Ortho Pharmaceutical Corporation. |
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*Reprint requests: Harry H. Sharata, MD, PhD, University Station Clinics, 2880 University Ave. Madison, WI 53705. |
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0190-9622/97/$5.00 + 0 16/4/78246 |
Vol 36 - N° 5S
P. 869-871 - mai 1997 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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