Mastication of verruca vulgaris associated with esophageal papilloma: HPV-45 sequences detected in oral and cutaneous tissues - 11/09/11
From the Department of Dermatologya and the Department of Internal Medicine Section of Gastroenterology,b University of Texas Medical School at Houston; and the Departments of Microbiology and Immunology,c and Dermatology,d University of Texas Medical Branch, Galveston.
Abstract |
Human papillomaviruses (HPVs) are double-stranded, circular, epitheliotropic DNA viruses of which nearly 70 types have been identified. Specific HPV types exhibit a predilection to infect certain sites; however, occurrence is not unique or restricted to these sites. HPV typing may also be helpful in determining the oncogenic potential of HPV lesions. The most common HPV types, 6 and 11, are associated with benign mucosal lesions, whereas types 18, 16, 31, and 33 are thought to confer a high rate of malignant transformation. We describe a patient with both palmar verrucae and esophageal papillomatosis that proved to be HPV type 45 by polymerase chain reaction. HPV 45 has a high homology to HPV 18 and is a member of the relatively new "high-risk" mucosal HPV family in terms of cervical oncogenic potential. To our knowledge, HPV 45 has never been reported in cutaneous warts or esophageal lesions.(J Am Acad Dermatol 1997;36:853-7.)
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 | This article is made possible through an educational grant from the Dermatological Division, Ortho Pharmaceutical Corporation. |
| Reprint requests: Stephen K. Tyring, MD, PhD, University of Texas Medical Branch, Department of Dermatology, Galveston, TX 77555-0783. |
 | 0190-9622/97/$5.00 + 0 16/4/77225 |
Vol 36 - N° 5S
P. 853-857 - mai 1997 Retour au numéro
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