SINUSITIS IN HIV INFECTION - 09/09/11

Doi : 10.1016/S0889-8561(05)70306-4

Catherine B. Small, MD ^{^{*
From the Department of Medicine, Divisions of Infectious Diseases (CBS) and Allergy/Immunology (DLR), Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York}}, David L. Rosenstreich, MD ^{^{*
From the Department of Medicine, Divisions of Infectious Diseases (CBS) and Allergy/Immunology (DLR), Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York}}

Résumé

The number of human immunodeficiency virus (HIV)–infected outpatients is growing rapidly because of the widespread use of antiretroviral therapy, earlier recognition of HIV infection and prophylaxis, and earlier treatment of opportunistic infections.^{56 Small C.B., Kaufman A., Armenaka M. , et al. Sinusitis and atopy in human immunodeficiency virus infection J Infect Dis 1993 ; 167 : 283-290

Cliquez ici pour aller à la section Références} As a result, new HIV-associated medical problems are being encountered with increasing frequency. Among the most important of these are chronic and recurrent sinusitis. Based on several prospective studies, the incidence of sinusitis in HIV-infected patients is estimated to be as high as 60% to 80%.^{27 Lamprecht J., Wiedbrauk C. Sinusitis und andere typische Erkranken-gun im HNO-Bereich im Rahmen des erworbene Immundefekt-syndroms (AIDS) HNO 1988 ; 36 : 489-492

Cliquez ici pour aller à la section Références, 53 Sample S., Lenahan G.A., Serwonska M.H. , et al. Allergic diseases and sinusitis in acquired immune deficiency syndrome (AIDS) J Allergy Clin Immunol 1989 ; 83 : 190

Cliquez ici pour aller à la section Références} In addition, HIV-infected patients may have an atypical presentation of sinusitis that makes recognition difficult for many practitioners. Because of the associated immunodeficiency in HIV infection, sinusitis often tends to be more severe and difficult to treat than in non–HIV-infected subjects. For these reasons, sinusitis has become a major source of morbidity in HIV-infected patients and is likely to become more of a problem for as long as the HIV epidemic persists. This article reviews the current state of knowledge about sinusitis in HIV infection, including its epidemiology, clinical presentation, pathophysiology, and current recommendations for treatment and management.

Le texte complet de cet article est disponible en PDF.

Plan

Address reprint requests to Catherine B. Small, MD, Department of Medicine, Division of Infectious Diseases, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467
This research was supported by Grant AI-29871 from the National Institutes of Health and the Albert Einstein College of Medicine Cancer Center Grant P30-CA-13330.