Modification in serum concentrations of aminoterminal propeptide of type III procollagen in patients with previous transmural myocardial infarction - 09/09/11
Abstract |
The aim of our study was to evaluate the modification of serum concentration of aminoterminal propeptide of type III procollagen (PIIINP) in 70 patients with previous transmural myocardial infarction. In 38 patients (group 1) PIIINP levels increased at 6 and 12 months after infarction; in 32 patients (group 2) PIIINP increased at 6 months, returning to baseline at 12 months. At the same time we observed a significant left ventricular enlargement and worsening of the performance in group 1, whereas in group 2 an improvement was seen in left ventricular volumes and performance. In conclusion, rearrangement of collagen myocardial matrix plays an important role in left ventricular postinfarction modification. This process can be easily followed over time in a noninvasive manner by dosing serum PIIINP concentrations. (Am Heart J 1998;135:287-92.)
Le texte complet de cet article est disponible en PDF.Plan
 | From the aInstitute of Cardiology, Department of Internal Medicine, University of Modena, the bDepartment of Nuclear Medicine, Fondazione Clinica del Lavoro, Sezione di Pavia, Pavia, and the cDepartment of Biomedical Sciences, University of Modena. |
| Supported by grant of CNR (Consiglio Nazionale delle Ricerche), FATMA project No. 95.00859.PF41. |
 | Reprint requests: Maria Grazia Modena, MD, Institute of Cardiology, Department of Internal Medicine, Policlinico - Via del Pozzo 71, 41100 Modena, Italy. |
| 4/1/86019 |
Vol 135 - N° 2
P. 287-292 - février 1998 Retour au numéro
Article précédent
- Enhanced coagulation activation in troponin T–positive unstable angina pectoris
- Wolfram Terres, Petra Kümmel, Anja Sudrow, Hilke Reuterb, Thomas Meinertz, Christian W. Hamm
- Prehospital delay in patients with acute coronary heart disease: Concordance between patient interviews and medical records
- Robert J. Goldberg, Paul G. McGovern, Thomas Guggina, Judith Savageau, Wayen D. Rosamond, Russell V. Luepker
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?