Noninvasive evaluation of myocardial ischemia in Kawasaki disease: Comparison between dipyridamole stress thallium imaging and exercise stress testing - 09/09/11
Abstract |
The sensitivities of dipyridamole stress thallium 201 single photon emission computed tomography (SPECT) and treadmill exercise testing in the detection of myocardial ischemia were compared. Thirty-eight patients with Kawasaki disease and 11 age-matched controls participated in the study. Fifteen of the 38 patients with Kawasaki disease had marked coronary artery stenosis (>75%) in at least one vessel. SPECT scans were obtained immediately after dipyridamole infusion and 4 hours later. The sensitivity of SPECT for detection of coronary stenosis was 80% (12/15), whereas that of treadmill exercise testing was only 33% (5/15) (p < 0.001). Although the sensitivity of SPECT significantly exceeded that of treadmill exercise testing among patients with coronary stenosis in only one vessel (p < 0.05), such benefits were not found for patients with stenosis in two or three vessels. These findings suggest that dipyridamole stress SPECT has a higher degree of sensitivity in the detection of myocardial ischemia than does treadmill exercise testing, especially for patients with single-vessel disease. (Am Heart J 1998;135:482-7.)
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 | From the Departments of Pediatrics and aRadiology, Kurume University School of Medicine. |
| Supported in part by grant-in-aid 05770579 for encouragement of young scientists from the Ministry of Education, Science and Culture, Tokyo, Japan. |
 | Reprint requests: Tsuyoshi Fukuda, MD, Division of Pediatric Cardiology, Kinki University School of Medicine, 377-2, Ohno-higashi, Osaka-Sayama, Osaka, 589, Japan. |
| 0002-8703/98/$5.00 + 0 4/1/86038 |
Vol 135 - N° 3
P. 482-487 - mars 1998 Retour au numéro
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