Occupational asthma by Anisakis simplex - 09/09/11
Abstract |
Background: No cases of occupational asthma caused by the inhalation of antigens from Anisakis simplex have been published. Objective: The purpose of this study was to evaluate the possibility that A simplex can play a role in the asthma experienced by 2 workers when handling fish and fish flour. Methods: Skin prick and bronchial challenge tests with A simplex were performed. We also carried out measurements of specific IgE to A simplex and immunoblotting. Results: Both patients had strong positive skin test responses, challenge test responses, and specific IgE to A simplex . Immunoblotting showed that both patients also had IgE against several bands in the fish flour extract, suggesting contamination by Anisakis allergens. Conclusion: These 2 patients provide evidence for occupational asthma caused by A simplex , based on in vivo and in vitro tests for Anisakis-specific IgE. (J Allergy Clin Immunol 1998;102:831-4.)
Le texte complet de cet article est disponible en PDF.Keywords : Anisakis simplex, occupational asthma, allergy to fish, fish flour
Abbreviations : AS:, PEFR:
Plan
![]() | From a Servicios de Alergia y Bioquímica del Hospital Rio Hortega, Valladolid; and b ALK-ABELLO, Madrid. |
![]() ![]() | Reprint requests: A. Armentia, Hospital Rio Hortega, Cardenal Torquemada, s.n., 47010 Valladolid, Spain. |
![]() | 0091-6749/98 $5.00 + 0 1/1/93398 |
Vol 102 - N° 5
P. 831-834 - novembre 1998 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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