Evaluating wrist injuries in the emergency department (ED) is facilitated by a thorough working knowledge of surface and functional anatomy, injury mechanism, and radiologic nuances as well as an understanding of the limitations of the physical examination and radiographic studies. The physical examination can be more reliable than radiographs in some conditions, although swelling and generalized pain often limit the examination's reliability. Knowing the pattern of injury associated with mechanisms frequently helps in interpreting unusual radiographs. Special radiographic views can be crucial in disclosing an occult fracture or ligamentous injury.^{*The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, the Department of Defense, or the US government.}