Auditory brainstem response findings in Rett syndrome: Stability over time - 05/09/11
Abstract |
Objective: To determine whether changes consistent with the presence of white matter neurodegenerative disease would be observed in the auditory brainstem response (ABR) in Rett syndrome in conjunction with age advancement. Study design: Initial and follow-up ABR findings were analyzed in a sample of 27 female patients with Rett syndrome. The interval between ABR tests ranged from 1 to 9 years. Results: No significant group differences consistent with neurodegenerative disease were observed in the wave I-III, III-V, or I-V interpeak latency intervals between the initial and follow-up test sessions. Conclusions: Rett syndrome is not a disorder characterized by progressive white matter degeneration affecting the integrity of the brainstem central auditory pathways. (J Pediatr 2000;137:393-6)
Le texte complet de cet article est disponible en PDF.Abbreviations : ABR, IPLI
Plan
 | Supported by National Institutes of Health grant HD24448 entitled, Pathogenesis of Rett Syndrome, and Johns Hopkins Pediatric Clinical Research grant RR-00052 to Dr. Naidu. |
| Reprint requests: Joseph P. Pillion, PhD, Department of Audiology, 707 North Broadway, Kennedy Krieger Institute, Baltimore, MD 21205. |
Vol 137 - N° 3
P. 393-396 - septembre 2000 Retour au numéro
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