Association between folic acid food fortification and congenital orofacial clefts - 29/08/11
Doi : 10.1067/S0022-3476(03)00495-5
Joel G Ray, MD, FRCPC, MSc ⁎ 
, Chris Meier, BSc, Marian J Vermeulen, BScN, MHSc, Philip R Wyatt, MD, FRCPC, PhD, David E.C Cole, MD, FRCPC, PhD
, Chris Meier, BSc, Marian J Vermeulen, BScN, MHSc, Philip R Wyatt, MD, FRCPC, PhD, David E.C Cole, MD, FRCPC, PhD From the Division of Obstetrical Medicine and Prehospital Care Programme, Sunnybrook and Women's College Health Sciences Centre, and the Departments of Laboratory Medicine and Pathobiology, Medicine, and Paediatrics (Genetics), University of Toronto; and the Ontario Maternal Serum Screening Database Department, Genetics Programme, and the Department of Genetics, North York General Hospital, Toronto, Ontario, Canada
Reprint requests: Joel G. Ray, MD, FRCPC, MSc, Inner City Health Research Unit, Dept of Medicine, St Michael's Hospital, Toronto, Ontario M5B 1W8, Canada.Abstract |
By January 1998, most of Canada's cereal grain products were being fortified with folic acid. Among 336,963 women who underwent antenatal maternal serum screening, the prevalence of orofacial clefts did not change from before (1.15 per 1000) to after (1.21 per 1000) food fortification (prevalence ratio, 1.06; 95% confidence interval, 0.86–1.30).
Le texte complet de cet article est disponible en PDF.Abbreviations : CI, MSS, OFC, PR, RCT
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Vol 143 - N° 6
P. 805-807 - décembre 2003 Retour au numéro
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