Prominent mental (chin) crease: A new sign of pseudoxanthoma elasticum - 29/08/11
Abstract |
Pseudoxanthoma elasticum (PXE) is an inherited disease with many systemic complications. Its diagnosis can be easily overlooked. The purpose of this study was to assess a new clinical sign of PXE. A total of 47 consecutive patients with PXE were examined for mental creases and compared with 47 age-matched control patients. Photographs were evaluated by a blinded investigator. Mental creases were present in 43 of 47 patients with PXE, affected the majority of individuals in every age group, and were significantly more common than in control patients (P < .0001). Under the age of 30 years, two thirds of patients with PXE had mental creases whereas mental creases were not present in any age-matched control patients. Mental creases commonly occur in patients with PXE. In young patients they are a sensitive and highly specific physical finding of this disorder. The presence of exaggerated mental creases is, thus, a useful physical marker for PXE. (J Am Acad Dermatol 2003;48:620-2.)
Le texte complet de cet article est disponible en PDF.Plan
 | Funding sources: Supported by the Food and Drug Administration Orphan Products Development grant FD-R-002161-01 (to M. L.). |
| Conflict of interest: None identified. |
 | Reprint requests: Mark Lebwohl, MD, Mount Sinai School of Medicine, Box 1048, 1 Gustave L. Levy Pl, New York, NY 10029. E-mail: sinaiderm@aol.com. |
| 0190-9622/2003/$30.00 + 0 |
Vol 48 - N° 4
P. 620-622 - avril 2003 Retour au numéro
Article précédent
- Palpebral edema as a cutaneous manifestation of hyperthyroidism
- Tetsuya Higuchi, Takahiro Satoh, Hiroo Yokozeki, Ichiro Katayama, Kiyoshi Nishioka
- Neonatal pemphigus vulgaris: IgG4 autoantibodies to desmoglein 3 induce skin blisters in newborns
- Thomas Parlowsky, Julia Welzel, Masayuki Amagai, Detlef Zillikens, Thorsten Wygold
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?