Usefulness of quantitative echocardiographic techniques to predict recovery of regional and global left ventricular function after acute myocardial infarction - 28/08/11
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Abstract |
The left ventricular response to dobutamine may be quantified using tissue Doppler measurement of myocardial velocity or displacement or 3-dimensional echocardiography to measure ventricular volume and ejection fraction. This study sought to explore the accuracy of these methods for predicting segmental and global responses to therapy. Standard dobutamine and 3-dimensional echocardiography were performed in 92 consecutive patients with abnormal left ventricular function at rest. Recovery of function was defined by comparison with follow-up echocardiography at rest 5 months later. Segments that showed improved regional function at follow-up showed a higher increment in peak tissue Doppler velocity with dobutamine therapy than in nonviable segments (1.2 ± 0.4 vs 0.3 ± 0.2 cm/s, p = 0.001). Similarly, patients who showed a >5% improvement of ejection fraction at follow-up showed a greater displacement response to dobutamine (6.9 ± 3.2 vs 2.1 ± 2.3 mm, p = 0.001), as well as a higher rate of ejection fraction response to dobutamine (9 ± 3% vs 2 ± 2%, p = 0.001). The optimal cutoff values for predicting subsequent recovery of function at rest were an increment of peak velocity >1 cm/s, >5 mm of displacement, and a >5% improvement of ejection fraction with low-dose dobutamine.
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![]() | This study was supported in part by the National Health and Medical Research Council, Canberra, Australia, and by an equipment loan from GE-Vingmed Ultrasound, Horten, Norway. |
Vol 91 - N° 4
P. 391-396 - février 2003 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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