Transsacral exenteration of fixed primary and recurrent anorectal cancer - 26/08/11
Abstract |
Background |
Posteriorly fixed anorectal cancer is often considered incurable, but may be resectable using transsacral approaches.
Methods |
We reviewed 45 patients undergoing transsacral exenteration for this problem since 1983 to determine outcome of such surgery.
Results |
The group consisted of 38 men and 7 women; 17 had primary tumors, 28 had recurrent cancer: local excision, 1; low anterior resection, 11; or abdominoperineal resection, 16. Thirty-nine had prior XRT. Operative mortality was 4%. Severe pain was relieved in 16 of 22 (72%) patients. Crude recurrence rates are local 22%, local plus distant 11%, distant 16%. Five-year disease-free survival is 31% for primary disease, 32% for recurrence. Median survival is abdominoperineal resection recurrence, 24 months; primary cancer, 30 months; low anterior resection recurrence, 37 months.
Conclusions |
Transsacral exenteration relieved pain in 70% of patients with fixed anorectal cancer, and led to long-term survival in 31% to 32%. Prognosis trended toward benefit for recurrence after low anterior resection.
Le texte complet de cet article est disponible en PDF.Keywords : Anorectal cancer, Fixed, Transsacral exenteration
Plan
Vol 186 - N° 6
P. 670-674 - décembre 2003 Retour au numéro
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