Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B - 26/08/11
, Julian Munoz, MD, MSPH a, Joe Teague, MD a, Alfred Stanley, MD b, Vera Bittner, MD, MSPH cAbstract |
This study examined the accuracy of a triglyceride/high-density lipoprotein (HDL) cholesterol ratio of 3.8 for the prediction of low-density lipoprotein (LDL) phenotype B. The ratio of 3.8 was based on Adult Treatment Panel recommendations for normal fasting triglycerides (<150 mg/dl) and HDL cholesterol (>40 mg/dl). Fasting blood samples were obtained from 658 patients. LDL phenotype analysis was performed by nuclear magnetic resonance spectroscopy. A triglyceride/HDL cholesterol ratio of 3.8 divided the distribution of LDL phenotypes with 79% (95% confidence interval [CI] 74 to 83) of phenotype B greater than and 81% (95% CI 77 to 85) of phenotype A less than the ratio of 3.8. The ratio was reliable for identifying LDL phenotype B in men and women.
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Vol 94 - N° 2
P. 219-222 - juillet 2004 Retour au numéro
Article précédent
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- George A Bray, William M Vollmer, Frank M Sacks, Eva Obarzanek, Laura P Svetkey, Lawrence J Appel, DASH Collaborative Research Group
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