Evaluation of a high-dose dexamethasone-eluting stent - 26/08/11
Doi : 10.1016/j.amjcard.2004.03.061
Rainer Hoffmann, MD a, ⁎ 
, Roswitha Langenberg, RN, Peter Radke, MD a, Andreas Franke, MD a, Rüdiger Blindt, MD a, Jan Ortlepp, MD a, Jeff J Popma, MD b, Christian Weber, MD c, Peter Hanrath, MD a, *
, Roswitha Langenberg, RN, Peter Radke, MD a, Andreas Franke, MD a, Rüdiger Blindt, MD a, Jan Ortlepp, MD a, Jeff J Popma, MD b, Christian Weber, MD c, Peter Hanrath, MD a, * a Medical Clinic I, University Hospital Aachen, Germany
b Angiographic Core Laboratory, Brigham & Women's Hospital, Boston, Massachusetts, USA
c Department of Molecular Biology, University Aachen, Aachen, Germany
*Dr. Hoffman's address is: Medical Clinic I, University RWTH Aachen, Pauwelsstraβe 30, 52057 Aachen, Germany.
Abstract |
This study evaluated the safety and efficacy of a dexamethasone-eluting stent with a special high dexamethasone-loading dose for treatment of de novo coronary lesions in 30 patients. Eight patients had in-stent restenosis (restenosis rate 31%) at 6-month follow-up, and the in-stent late lumen loss was 0.96 ± 0.63 mm due to an average intimal hyperplasia area obstruction of 32 ± 21%, indicating that high-dose dexamethasone-loaded stents do not significantly reduce neointimal proliferation.
Le texte complet de cet article est disponible en PDF. | This study was supported by a grant from Abbott Vascular Devices, Redwood City, California. |
© 2004
Excerpta Medica Inc. Tous droits réservés.
Vol 94 - N° 2
P. 193-195 - juillet 2004 Retour au numéro
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