Effect of chronic heart failure on nuclear factor kappa B in peripheral leukocytes - 26/08/11
Doi : 10.1016/j.amjcard.2004.05.041
Stefan Frantz, MD a, ⁎ 
, Stefan Stoerk, MD b, Sami Ok a, Helga Wagner a, Christiane E. Angermann, MD b, Georg Ertl, MD a, Johann Bauersachs, MD a
, Stefan Stoerk, MD b, Sami Ok a, Helga Wagner a, Christiane E. Angermann, MD b, Georg Ertl, MD a, Johann Bauersachs, MD a a Medizinische Klinik
b Medizinische Poliklinik der Universität Würzburg, Germany
*Dr. Frantz's address is: Medizinische Universitätsklinik Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany
Résumé |
Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor activated by various stimuli that are implicated in the progression of chronic heart failure. Therefore, we examined the activation of NF-κB in peripheral leukocytes, the only nucleated cell population noninvasively accessible in patients with heart failure. In patients with stable heart failure with no obvious other reason for NF-κB activation, NF-κB was significantly activated.
Le texte complet de cet article est disponible en PDF.| This work was supported by the Deutsche Forschungsgemeinschaft (Fr. 1377/4-3), Bonn, Germany. |
© 2004
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Vol 94 - N° 5
P. 671-673 - septembre 2004 Retour au numéro
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