Common variable immune deficiency with gastrointestinal graft versus host disease - 25/08/11
Abstract |
Rationale |
AS, a 22 year-old female, was diagnosed with Common Variable Immune Deficiency Syndrome at age 19 years-old after many years of symptoms including chronic anemia and thrombocytopenia requiring multiple transfusions, empyema and chronic cutaneous fungal infections.
Methods |
Her IgG at the time of diagnosis was 249 mg/dl. Recently, due to persistent gastrointestinal complaints, an evaluation was undertaken to determine an etiology.
Results |
Her ensuing workup, and eventual intestinal biopsy, revealed the diagnosis of gastrointestinal graft versus host disease. The patient had received only type-matched blood products with her transfusions in the past.
Conclusions |
Exposing patients to blood or its products is not without some inherent risks. These risk range from exposure to infectious agents, such as hepatitis or HIV, to immune mediated reactions leading to hemolysis. Fortunately modern screening techniques are quite good at identifying these risk factors and help minimize complications. However, not all potential complications have been identified. We present a case of post-transfusion gastrointestinal graft versus host disease in a patient with common variable immune deficiency syndrome
Le texte complet de cet article est disponible en PDF. Funding: Self-funded |
Vol 113 - N° 2S
P. S125 - février 2004 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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