Screening for post-miscarriage psychiatric morbidity - 25/08/11
, Dominic T.S. Lee, MD b, Shing-Kai Yip, MD a, Daniel Shek, PhD c, Wing H. Tam, MRCOG a, Tony K.H. Chung, MD a
Reprint requests: Dr Ingrid H. Lok, Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.Abstract |
Objective |
The purpose of this study was to evaluate 12-item General Health Questionnaire (GHQ-12) in screening for psychiatric morbidity after miscarriage.
Study design |
A prospective cohort study was carried out involving 222 patients. Six weeks after miscarriage, the GHQ-12 was applied. Psychiatric “case” or “non-case” was diagnosed by the psychiatrist with use of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-III-R. The patients were computer randomized into Groups A or B. A receiver operating characteristic (ROC) curve was constructed for Group A. The optimal cutoff value of GHQ-12 was determined, and this value was applied to Group B. The test characteristics were assessed.
Results |
Twenty-seven patients were found to be psychiatric cases. An ROC with area under curve of 0.93 (95% CI 0.87-0.99, P<.001) was constructed. The best GHQ-12 cutoff score was ≥4 in detecting psychiatric caseness. A sensitivity of 83%, specificity of 90%, positive predictive value of 50%, and negative predictive value of 98% were obtained.
Conclusion |
GHQ-12 is an effective screening tool in detecting psychiatric morbidity after miscarriage.
Le texte complet de cet article est disponible en PDF.Keywords : Miscarriage, GHQ-12, Psychiatric morbidity, Depression, Screening
Plan
Vol 191 - N° 2
P. 546-550 - août 2004 Retour au numéro
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