Preterm twins: What threshold of birth weight discordance heralds major adverse neonatal outcome? - 25/08/11
Reprint requests: Alessandro Ghidini, MD, Department of Obstetrics and Gynecology, Georgetown University Hospital-3PHC, 3800 Reservoir Rd, NW, Washington, DC 20007.Résumé |
Objective |
This study was undertaken to establish the optimal threshold of birth weight discordance for prediction of adverse outcome in liveborn, nonmalformed preterm twins.
Study design |
We accessed a cohort of twin gestations for the period 1990 through 2000 delivered at less than 37.0 weeks' gestation. Adverse neonatal outcome was defined as stillbirth or occurrence of major morbidities.
Results |
A total of 335 twin gestations (670 twins) were included, of which 104 (31%) experienced adverse neonatal outcome. The average birth weight discordance was 12.4% ± 10.6% versus 19.4% ± 14.8% in those with good versus adverse outcome (P < .001). Birth weight discordance was a significant predictor of adverse neonatal outcome that was independent of gestational age at delivery, small for gestational age, and chorionicity. Receiver operating characteristic curve analysis suggested that optimal thresholds of birth weight discordance for clinical use should take into account gestational age.
Conclusion |
Birth weight discordance is an independent predictor of adverse neonatal outcome in liveborn, nonmalformed preterm twins.
Le texte complet de cet article est disponible en PDF.Key words : Twins, Birth weight discordance, Preterm delivery
Plan
| Presented at the Twenty-Fourth Annual Meeting of the Society for Maternal-Fetal Medicine, February 2-7, 2004, New Orleans, La. |
Vol 191 - N° 4
P. 1441-1445 - octobre 2004 Retour au numéro
Article précédent
- Clinical significance of first trimester crown-rump length disparity in dichorionic twin gestations
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