Randomized trial of systemic hypothermia selectively protects the cortex on MRI in term hypoxic-ischemic encephalopathy - 24/08/11
Doi : 10.1016/j.jpeds.2004.07.034
Terrie E. Inder, MB, ChB, MD ⁎ 
, Rod W. Hunt, MB, BS, Colin J. Morley, MB, BS, MD, Lee Coleman, MB, ChB, Michael Stewart, MB, BS, Lex W. Doyle, MB, BS, MD, Susan E. Jacobs, MB, BS
, Rod W. Hunt, MB, BS, Colin J. Morley, MB, BS, MD, Lee Coleman, MB, ChB, Michael Stewart, MB, BS, Lex W. Doyle, MB, BS, MD, Susan E. Jacobs, MB, BS From the Division of Newborn Services, Royal Women's Hospital, Neonatal Neurology, Royal Children's Hospital, Murdoch Children's Research Institute, University of Melbourne, Department of Medical Imaging, Royal Children's Hospital, and Departments of Obstetrics and Gynaecology, and Paediatrics, University of Melbourne, Melbourne, Australia
Reprint requests: Terrie Inder, Neonatal Neurology, 6th Floor, Royal Children's Hospital, Flemington Rd, Parkville, 3052, Australia.See editorial, p 723, and related article, p 832.
Abstract |
Twenty-six infants with hypoxic-ischemic encephalopathy (HIE) were randomized to normothermia or to systemic hypothermia. The hypothermia group had less cortical gray matter signal abnormality on magnetic resonance imaging (MRI) (1/12 vs 7/14 infants in the normothermic group; P=.036), which may indicate differing regional benefit from systemic hypothermia.
Le texte complet de cet article est disponible en PDF.Mots-clés : DNG, EEG, HIE, MRI
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| Supported by the Australian National Health and Medical Research Council (NHMRC Study No: 216725). |
© 2004
Elsevier Inc. Tous droits réservés.
Vol 145 - N° 6
P. 835-837 - décembre 2004 Retour au numéro
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