Richardson score predicts short-term adverse respiratory outcomes in newborns ≥34 weeks gestation - 24/08/11
, Susan M. Shaheen, MS, Emily M. Breed, BA, Carlos Botas, MD, John D. Greene, MA, Cathleen K. Yoshida, MS, John Zupancic, MD, ScD, Thomas B. Newman, MD, MPH
Reprint requests: Gabriel J. Escobar, MD, Permanente Medical Group, Division of Research, 2000 Broadway, Oakland, CA 94612.Abstract |
Objectives |
To develop a model to predict which newborns ≥34 weeks gestation with respiratory distress will die or will require prolonged (>3 days) assisted ventilation.
Methods |
Retrospective cohort study using data from Northern California newborns ≥34 weeks gestation who presented with respiratory distress. We split the cohort into derivation and validation datasets. Bivariate and multivariate data analyses were performed on the derivation dataset. After developing a simple score on the derivation dataset, we applied it to the original as well as to a second validation dataset from Massachusetts.
Results |
Of 2276 babies who met our initial eligibility criteria, 203 (9.3%) had the primary study outcome (assisted ventilation >3 days or death). A simple score based on gestational age, the lowest PaO2/FIO2, a variable combining lowest pH and highest PaCO2, and the lowest mean arterial blood pressure had excellent performance, with a c-statistic of 0.85 in the derivation dataset, 0.80 in the validation dataset, and 0.80 in the secondary validation dataset.
Conclusions |
A simple objective score based on routinely collected physiologic predictors can predict respiratory outcomes in infants ≥34 weeks gestation with respiratory distress.
Le texte complet de cet article est disponible en PDF.Mots-clés : CPAP, ECMO, ICD, IMV, INO, KPMCP, LOAV, NICU, SAS, SNAP-II
Plan
| Presented at a poster session at the May 2003 meetings of the Society for Pediatric Research. This project was supported by The Permanente Medical Group, Inc, and Kaiser Foundation Health Plan, Inc. |
Vol 145 - N° 6
P. 754-760 - décembre 2004 Retour au numéro
Article précédent
- Heat Loss Prevention (HeLP) in the delivery room: A randomized controlled trial of polyethylene occlusive skin wrapping in very preterm infants
- Sunita Vohra, Robin S. Roberts, Bo Zhang, Marianne Janes, Barbara Schmidt
- Rapid advancement to more concentrated formula in infants after surgery for congenital heart disease reduces duration of hospital stay: A randomized clinical trial
- Francy Pillo-Blocka, Ian Adatia, Waseem Sharieff, Brian W. McCrindle, Stanley Zlotkin
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?