Generic and additional names: Moxifloxacin Hydrochloride

CAS name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride

CAS registry #: 186826-86-8

Molecular formula: C₂₁H₂₄FN₃O₄·HCl

Molecular weight: 437.89

Intellectual property rights: Bayer

Brand names: Actimax (Sankyo); Actira (Bayer); Avelox (Bayer); Octegra (Bayer); Proflox (Esteve); Vigamox

(Alcon)

Derivatives: Moxifloxacin is a quinolone/fluoroquinolone antibiotic related to ciprofloxacin, enoxacin, fleroxacin, gatifloxacin, gemifloxacin, grepafloxacin, levofloxacin, lomefloxacin, norfloxacin, ofloxacin, pefloxacin, prulifloxacin, rufloxacin, sparfloxacin, temafloxacin, trovafloxacin, sitafloxacin

Solubility: Soluble in water

Polarity: Log P 2.033 [DrugBank]

Melting point: 238–242ºC [DrugBank]

Formulation and optimal human dosage: Avelox tablets: containing moxifloxacin hydrochloride (equivalent to 400 mg moxifloxacin).

Avelox i.v.: 250 ml latex-free flexibags as a sterile, preservative-free, 0.8% sodium chloride aqueous solution of moxifloxacin hydrochloride (containing 400 mg moxifloxacin).

400 mg daily dose