Tumor fragment impacted at the major duodenal papilla causing obstructive jaundice in a patient with hepatocellular carcinoma - 23/08/11
| Commentary |
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| Obstructive jaundice is an uncommon presentation of HCC, occurring in fewer than 10% of patients. Such obstruction may be caused by tumor infiltration, duct compression, and tumor casts or blood clots within the ductal system. In some cases of hemobilia, the diagnosis of HCC is only made after histologic evaluation of the blood clot reveals it to contain HCC cells. TACE understandably may increase the possibility of common bile duct obstruction because it allows bits of the tumor to fragment off the main mass when it becomes necrotic. This case echoes Virgil’s prescient statement aegrescit medendo (the disease worsens with treatment), although advances in treatment subsequent to his time (70-19 B.C.E.) have enabled us to treat the complications of our treatments, albeit with the potential for further complications. And so it goes…. |
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| Lawrence J. Brandt, MD |
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| Associate Editor for Focal Points |
Vol 68 - N° 5
P. 999-1000 - novembre 2008 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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