Pseudodiverticulosis with eosinophilic esophagitis: first reported case - 22/08/11
Doi : 10.1016/j.gie.2007.06.049
| Commentary First reported by Mendel in 1960, intramural pseudodiverticulosis (IP) is an uncommon entity characterized by many small, flask-like outpouchings in the esophageal wall. IP may be segmental or diffuse and is commonly associated with esophageal motor abnormalities such as achalasia or esophageal spasm, but may also be seen associated with a variety of esophageal disorders including candidiasis, corrosive ingestion, stricture, Plummer-Vinson syndrome, and carcinoma. This case expands the associations to include eosinophilic esophagitis, but this should not be a surprise because we are increasingly diagnosing this disorder. Pseudodiverticula arise from the excretory ducts of the esophageal submucosal glands, usually in the setting of esophageal inflammation and stasis. While the exact cause of IP is unknown, in some cases it is possibly due to debris deposits in the ducts, which obstruct and expand them, or perhaps the glands dilate as a result of increased intraluminal pressure proximal to a luminal obstruction. In this patient, with both a chronic inflammatory process (eosinophilic esophagitis) and a solid-food obstructing esophageal stricture, 1, both, or none of the disorders could have been causative. Lawrence J. Brandt, MD Associate Editor for Focal Points |
© 2007
American Society for Gastrointestinal Endoscopy. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 66 - N° 6
P. 1223-1224 - décembre 2007 Retour au numéro
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