Hyperplastic polyp arising from heterotopic gastric epithelium in the esophagus - 22/08/11
Doi : 10.1016/j.gie.2007.06.025
Lawrence J. Brandt, MD, Editor, At the Focal Point Section
| Commentary Esophageal heterotopic gastric mucosa (HGM) occurs in approximately 0.1% to 10% of upper endoscopic evaluations and is thought to represent an embryologic failure of bidirectional replacement of esophageal columnar epithelium by squamous mucosa starting at the level of the midesophagus. Indeed, HGM has been reported throughout the GI tract. In the stomach, acid production by parietal cells within HGM can lead to ulcers, strictures, and webs; dysplasia and even cancer, while known to occur, are rare. It also is rare that hyperplastic polyps arise from esophageal HGM, and dysplasia in such polyps has not been described. Although surface erosion makes the diagnosis of dysplasia difficult, the focally prominent p53 staining in this case does suggest low-grade dysplasia within the polyp and reflects the potential for progressive neoplastic transformation. Lawrence J. Brandt, MD Associate Editor for Focal Points |
© 2007
American Society for Gastrointestinal Endoscopy. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 66 - N° 6
P. 1221-1222 - décembre 2007 Retour au numéro
Article précédent
- A novel endoscopic suturing technique using a specially designed so-called “8-ring” in combination with resolution clips (with videos)
- Takahiro Fujii, Akiko Ono, Kuang-I Fu
- Pseudodiverticulosis with eosinophilic esophagitis: first reported case
- Catherine M. Tsai, James Butler, Brooks D. Cash
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?