Self-expanding metallic stents for gastric outlet obstruction resulting from stomach cancer: a preliminary study with a newly designed double-layered pyloric stent - 22/08/11
Reprint requests: Dae Hwan Kang, MD, Department of Internal Medicine, Pusan National University College of Medicine, 1-10 Ami-dong, Seo-Gu, Busan 602-739, Korea.Busan, Korea
Abstract |
Background |
Although endoscopic stent placement is now generally accepted as a palliative treatment for gastric outlet obstruction resulting from gastric cancer, it carries potential limitations such as tumor ingrowth or migration.
Objective |
Our purpose was to evaluate the technical and clinical efficacy of endoscopic placement of a newly designed double-layered combination pyloric stent.
Design |
Prospective, uncontrolled, single-center.
Setting |
Tertiary referral university hospital.
Patients |
Eleven patients with gastric outlet obstruction by unresectable stomach cancer.
Interventions |
Eleven patients received a double-layered combination pyloric stent (an outer uncovered stent to reduce migration and an inner polytetrafluoroethylene-covered stent to prevent tumor ingrowth).
Main Outcome Measurement |
To evaluate technical success, clinical success, and complications, especially tumor ingrowth and migration.
Results |
Technical success was achieved in 11 of 11 (100%) patients. Among 11 patients in whom endoscopic stenting was placed successfully, clinical success was 90.9%, tumor ingrowth 0%, migration 9.1%, and tumor overgrowth 9.1%. Median stent patency period was 121 days.
Limitations |
Small number of patients, uncontrolled study, short-term follow-up period.
Conclusions |
We have described a technique for endoscopic metal stent placement by using the newly designed double-layered combination stent for gastric outlet obstruction by stomach cancer. This stent seems to be effective and looks promising for technical efficacy, clinical outcome, and preventing tumor ingrowth and migration.
Le texte complet de cet article est disponible en PDF.Abbreviations : GOOSS, PTFE, SEMS
Plan
Vol 66 - N° 6
P. 1206-1210 - décembre 2007 Retour au numéro
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