Protein-losing enteropathy from eosinophilic enteritis diagnosed by wireless capsule endoscopy and double-balloon enteroscopy - 22/08/11
Commentary In this patient, PLE, steatorrhea, and eosinophilia/EE comprise a triad of abnormalities that suggests small-bowel mucosal/submucosal disease, the cause of which is yet unknown; infection, immunologic disorders, neoplasia, and mediations are among the main culprits, but these seem to have been excluded. It is curious that a small-bowel series and push enteroscopy were unremarkable; that capsule enteroscopy led to double-balloon endoscopy-targeted biopsy specimens gives a view of the future approach to endoscopic diagnosis of small-bowel diseases. EE rarely is accompanied by both steatorrhea and PLE, the latter diagnosed by an elevated alpha-1 antitrypsin clearance. Although not widely available, nuclear studies that use labeled human serum albumin can be used to locate the site of protein loss and to follow response to therapy. Eos, the Greek goddess of the dawn, after whom the rosy-colored eosinophil is named, would be proud that endoscopic lighting was used to facilitate the condition associated with her name. At the close of each night, Eos ascends to heaven on a chariot drawn by 2 swift horses (Lampus and Phaëton), to announce the coming light of the sun. Think of that the next time you are coming in to make rounds and you gaze up at the early morning sky. Lawrence J. Brandt, MD Associate Editor for Focal Points |
Vol 65 - N° 6
P. 917-918 - mai 2007 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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