Benign Neoplasms of the Salivary Glands - 22/08/11
Key Points |
• | The salivary gland neoplasms are uncommon and generally benign. |
• | Most benign tumors can be easily cured by wide local excision, but pleomorphic adenoma, which is the most common salivary gland tumor, has a propensity for local recurrence. Simple enucleation is discouraged. |
• | The parotid gland is the most frequently affected major salivary gland, and the palate is the most commonly affected minor salivary gland location. |
• | Pleomorphic adenomas are the most common neoplasm of salivary glands, comprising 45% to 75% of all tumors in most series. These tumors typically affect patients in their 20s to 50s and there is a female predilection. |
• | Warthin’s tumor is the second most common tumor of the salivary glands and constitutes approximately 14% to 21% of salivary gland neoplasms. The tumor is almost exclusively found in the parotid gland, typically affects males in their 50s to 60s, and often may be bilateral. |
• | Basal cell adenomas are fairly uncommon benign tumors of the salivary glands and are divided into four major histologic subtypes: tubular, trabecular, solid, and membranous. |
• | Oncocytomas represent roughly 1% of all salivary gland tumors. They most commonly affect the parotid and occasionally the submandibular gland. Patients are typically in their 50s with a slight female predominance. |
• | Canalicular adenomas are rare and most commonly affect the minor salivary glands of the oral cavity, especially the upper lip. |
• | Myoepitheliomas are neoplasms that consist exclusively of myoepithelial cells. These component cells are believed to be one of the two component cells of pleomorphic adenomas. |
• | The roles of fine-needle aspiration biopsy and high-resolution imaging in the management of patients with salivary neoplasms continue to evolve. |
• | Deep lobe tumors require a total parotidectomy, with facial nerve preservation. Parapharyngeal tumors are most commonly excised through a cervical-parotid approach and only occasionally in conjunction with a mandibulotomy. |
Plan
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