Soft x-ray therapy for cutaneous basal cell and squamous cell carcinomas - 21/08/11
Reprint requests: Ludwig Suter, MD, In der Stroth 37, D-48157, Münster, Germany.Münster, Germany
Abstract |
Background |
We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment.
Objective |
We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations.
Methods |
Patients with 1267 consecutively irradiated (1988-1992) basal cell and squamous cell carcinomas were followed up (average 77 months).
Results |
The recurrence rate (5.1%) was related to tumor size and thickness and to the time-dose-fractionation factor. The frequency of ulcerations (6.3%) depended on field size, hardness of the x-rays, and in smaller fields (diameter up to 4 cm) on total dose, and time-dose-fractionation factor. Of all ulcerations, 82.5 % could be conservatively cured.
Limitations |
We have no evidence that our radiation schedule is superior to those published by other authors.
Conclusion |
These results verify the usefulness of soft x-ray therapy for cutaneous epithelial malignancies.
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| From Fachklinik Hornheide. Funding sources: None. Conflict of interest: None identified. |
Vol 53 - N° 6
P. 993-1001 - décembre 2005 Retour au numéro
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