Primary Sclerosing Cholangitis and Uveitis: A Case Series - 21/08/11
, Lyndell L. Lim, MBBS, FRANZCO a, R. Christopher Walton, MD b, Debra A. Goldstein, MD, FRCS(C) c, Brent Chalmers, MD a, James T. Rosenbaum, MD a
Inquiries to Lani T. Hoang, BS, Casey Eye Institute, Oregon Health and Science University, 3181 SW Sam Jackson Parkway, Portland, OR 97239Résumé |
Purpose |
To report the cases of six patients with primary sclerosing cholangitis and uveitis.
Design |
Retrospective observational case series.
Methods |
Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society.
Results |
Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five.
Conclusions |
Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.
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Vol 143 - N° 3
P. 534-536 - mars 2007 Retour au numéro
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