Retinal Pigment Epithelial Tear after Intravitreal Ranibizumab - 21/08/11
, Anna S. Kitzmann, MD
Inquiries to Sophie J. Bakri, MD, Department of Ophthalmology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905Résumé |
Purpose |
To report two cases of a retinal pigment epithelial (RPE) tear after intravitreal injection of 0.05 mg ranibizumab.
Design |
Observational case report.
Methods |
Two patients with choroidal neovascularization (CNV) resulting from age-related macular degeneration (AMD) were treated with an intravitreal injection of ranibizumab.
Results |
Both patients were found to have a RPE tear on follow-up visits at one month, confirmed by optical coherence tomography (OCT) and by fluorescein or indocyanine green angiography.
Conclusions |
RPE tears may occur after intravitreal injection of ranibizumab. Further study is needed to determine whether CNV membranes associated with pigment epithelial detachments (PED) are more likely to develop RPE tears after treatment with anti-vascular endothelial growth factor (anti-VEGF) agents.
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Vol 143 - N° 3
P. 505-507 - mars 2007 Retour au numéro
Article précédent
- Retinal Pigment Epithelium Tears Following Ranibizumab for Exudative Age-related Macular Degeneration
- Petros E. Carvounis, Andrew C. Kopel, Matthew S. Benz
- Intravitreal Bevacizumab for Idiopathic Choroidal Neovascularization After Previous Injection With Posterior Subtenon Triamcinolone
- Fumi Gomi, Kentaro Nishida, Yusuke Oshima, Hirokazu Sakaguchi, Miki Sawa, Motokazu Tsujikawa, Yasuo Tano
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