Cerebral injury in monochorionic twins with selective intrauterine growth restriction and/or birthweight discordance - 21/08/11
, Femke Slaghekke, MD b, Frank P. Vandenbussche, MD, PhD b, Johanna M. Middeldorp, MD, PhD b, Frans J. Walther, MD, PhD a, Dick Oepkes, MD, PhD b
Reprints: E. Lopriore, MD, PhD, Division of Neonatology, Department of Pediatrics, J6-S, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The NetherlandsRésumé |
Objective |
The objective of the study was to study the incidence of severe cerebral injury in monochorionic (MC) twins with selective intrauterine growth restriction (sIUGR) and/or birthweight discordance.
Study Design |
All MC twin pregnancies with 2 liveborn twins were included in the study. We excluded all cases with twin-to-twin transfusion syndrome (TTTS). Sequential cranial ultrasound scans were performed in all MC twin infants.
Results |
A total of 117 MC twin pairs were included in the study. The sIUGR of at least 1 fetus was found in 50 twin pregnancies (43%), and birthweight discordance of 25% or greater occurred in 26 twin pregnancies (22%). The overall incidence of severe cerebral injury was 3% (6/218). The incidence of severe cerebral injury in infants from twin pregnancies with and without sIUGR was 2% (2/94) and 3% (4/124), respectively (P = .62). The incidence of severe cerebral injury in infants with and without birthweight discordance was 0% (0/48) and 4% (6/170), respectively (P = .19).
Conclusion |
The incidence of severe cerebral injury in MC twin pregnancies not complicated by TTTS with 2 liveborn twins is low. No association could be demonstrated with sIUGR or intertwin birthweight discordance of 25% or greater.
Le texte complet de cet article est disponible en PDF.Key words : birthweight discordance, cerebral injury, monochorionic twins, selective intrauterine growth restriction
Plan
| Cite this article as: Lopriore E, Slaghekke F, Vandenbussche FP, et al. Cerebral injury in monochorionic twins with selective intrauterine growth restriction and/or birthweight discordance. Am J Obstet Gynecol 2008;199:628.e1-628.e5. |
Vol 199 - N° 6
P. null - décembre 2008 Retour au numéro
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