Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial - 21/08/11

Doi : 10.1016/j.ajog.2008.01.058

Isabelle Marc, MD, PhD ^a,^c, Pierre Rainville, PhD ^d,^f, Benoît Masse, PhD ^g, René Verreault, MD, PhD ^e^e, Lucie Vaillancourt, MD ^b, Estelle Vallée, MSc ^a, Sylvie Dodin, MD, MSc ^a,^d
^a Research Center, Hôpital St-François d'Assise (CHUQ), Quebec City, Canada
^b Department of Family Planning, Hôpital St-François d'Assise, Quebec City, Canada
^c Department of Pediatrics, Hôpital St-François d'Assise, Quebec City, Canada
^d Department of Obstetrics and Gynecology, Hôpital St-François d'Assise, Quebec City, Canada
^e Geriatrics Research Unit, Department of Epidemiology, Hôpital St-Sacrement, Université Laval, Quebec City, Canada
^f Department of Stomatology, Faculty of Dental Medicine, Université de Montréal, Montreal, QC, Canada
^g Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA

Résumé

Objective

The purpose of this study was to determine whether hypnotic analgesia can reduce the need for intravenous sedation analgesia without increasing pain and anxiety levels during abortion.

Study Design

A cohort of 350 women who were scheduled for surgical abortion (< 14 weeks' gestation) were assigned randomly to a standard care group or a group that received a standardized hypnotic analgesia intervention 20 minutes before and throughout the surgical procedure. Primary outcome was the difference between the 2 groups: (1) the proportion who received sedation (yes/no) during the surgical procedure and (2) self-assessments of pain and anxiety during suction evacuation of uterus content.

Results

Women who underwent hypnosis required less intravenous sedation analgesia (108/172 women; 63%) than the control group (149/175 women; 85%; P < .0001) and self-reported no difference in pain, but not in anxiety, levels during suction evacuation.

Conclusion

Hypnotic interventions can be effective as an adjunct to pharmacologic management of acute pain during abortion.

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Key words : anxiety, hypnosis, pain, pregnancy termination, randomized clinical trial

Plan

Materials and Methods

Patient characteristics

Outcomes

Comment

	Cite this article as: Marc I, Bainville P, Masse B, et al. Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial. Am J Obstet Gynecol 2008;199:469.e1-469.e9.
	Reprints not available from the authors.
	This study was supported by Canadian Institutes of Health Research (CHIR) grant MCT-68538. I. M. is the recipient of a PhD grant from the Fonds de Recherche en Santé du Québec.

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Vol 199 - N° 5

P. null - novembre 2008 Retour au numéro

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Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial - 21/08/11

Résumé

Objective

Study Design

Results

Conclusion

Plan

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