Management of Patients with a History of Allergy to Beta-Lactam Antibiotics - 20/08/11
Requests for reprints should be addressed to Anne B. Yates, MD, Division of Pediatric Allergy-Immunology, University of Mississippi Medical Center, Department of Pediatrics, 2500 North State Street, Jackson, MS 39216-4505.Abstract |
Patients with a history of penicillin allergy pose a treatment dilemma. Unnecessary avoidance of this relatively nontoxic class of drugs exposes the patient to potentially more toxic drugs, increases health care costs, and contributes to the development of antibiotic resistance. Yet for those who truly have allergy or other serious adverse reactions to beta-lactams, the use of alternate drugs is a must. This article reviews current management strategies to determine which patients are good candidates for reintroduction of beta-lactams and which patients should continue avoidance.
Le texte complet de cet article est disponible en PDF.Keywords : Adverse drug reaction, Beta-lactam allergy, Cephalosporin allergy, Desensitization, Drug allergy, Late hypersensitivity reaction, Penicillin allergy, Skin testing, Test dosing
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| Richard D. DeShazo, MD, Specialty Editor |
Vol 121 - N° 7
P. 572-576 - juillet 2008 Retour au numéro
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