Advances in environmental and occupational disorders - 20/08/11
, David B. Peden, MD, MS b
Reprint requests: Robert K. Bush, MD, William S. Middleton Veterans Administration Hospital, 2500 Overlook Terrace, Madison, WI 53705.Madison, Wis, and Chapel Hill, NC
Abstract |
As with the previous year, 2005 was a very active year for investigation of the effect of environmental agents on allergic disease, be they allergens, pollutants, bioaerosols, or occupationally encountered agents. There were a large number of articles on the prevalence of allergic disease in the United States, identification and characterization of a number of allergens, and the role of indoor allergens and potential mitigation of the effect of such allergens, as well as the hygiene hypothesis, air pollution, and the effect of these agents on airway disease. The Journal of Allergy and Clinical Immunology also saw very interesting case reports and mechanistic studies examining the causes of occupational immune-mediated disease. There were also reports on gene-environment interactions, highlighting the importance of such interactions in modulating the risk for development of allergic disease. That these interactions have proved to be remarkably complex comes as no surprise to the allergy and immunology community because allergists and immunologists have long appreciated the role of environmental influences on disease.
Le texte complet de cet article est disponible en PDF.Key words : Environment, allergens, asthma, occupational diseases, environmental controls
Abbreviations used : CBD, DEP, GSTM1, JACI, NHANES, PM, SNP
Plan
| Disclosure of potential conflict of interest: R. Bush has consultant arrangements with Ventria Bioscience, received grant support from the US Department of Veterans Affairs and the National Institutes of Health, and is employed by US Department of Veterans Affairs and the University of Wisconsin Medical Foundation. D. Peden has consultant arrangements with Merck, GSK, and Novartis; receives grant support from Genentech/Novartis and GSK; and is on the speakers’ bureau for Sepracor and GSK. |
Vol 117 - N° 6
P. 1367-1373 - juin 2006 Retour au numéro
Article précédent
- Biological material on inhaled coarse fraction particulate matter activates airway phagocytes in vivo in healthy volunteers
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- Which aspects of the farming lifestyle explain the inverse association with childhood allergy?
- Michael R. Perkin, David P. Strachan
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