Temporal Trends in the Use of Early Cardiac Catheterization in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes (Results from CRUSADE) - 20/08/11
, Eric D. Peterson, MD, MPH a, Jyotsna Mulgund, MS a, L. Kristin Newby, MD, MHS a, Jorge F. Saucedo, MD c, Neil S. Kleiman, MD d, Deepak L. Bhatt, MD e, Peter B. Berger, MD a, Christopher P. Cannon, MD g, David J. Cohen, MD h, Judith S. Hochman, MD i, E. Magnus Ohman, MD a, W. Brian Gibler, MD f, Robert A. Harrington, MD a, Sidney C. Smith, MD b, Matthew T. Roe, MD, MHS aCRUSADE Investigators
Corresponding author: Tel: 919-668-7536; fax: 919-668-7058.Résumé |
We evaluated temporal trends in the use of early (<48 hours) catheterization in patients with non–ST-segment elevation acute coronary syndromes with respect to baseline risk features since publication of the American College of Cardiology/American Heart Association guidelines, which include a class IA recommendation for an early invasive strategy for high-risk patients with non–ST-segment elevation acute coronary syndromes. Overall, we found that early catheterization use increased from 53% to 61% during the 3 years after the guidelines were released, but the increased use of early catheterization was highest (11%) in the group that was at lowest risk of predicted mortality, and it was lowest (6%) in the group at highest risk of predicted mortality who would potentially receive the most benefit from an aggressive treatment approach. In conclusion, despite the overall increase in the use of early catheterization, the gap between the use of an early invasive strategy in the highest and lowest risk patients remains large and tends to increase over time.
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| CRUSADE is funded by Schering-Plough Corporation, Kenilworth, New Jersey. Bristol-Myers Squibb (New York, New York)/Sanofi-Aventis Pharmaceuticals (Paris, France) Partnership provides additional funding support. Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts, also provided funding for this work. |
Vol 98 - N° 9
P. 1172-1176 - novembre 2006 Retour au numéro
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