Prostate brachytherapy seed implants occasionally embolize to lungs because of their small size. They may lodge in the right cardiac cavities before reaching the pulmonary arteries and lungs. A rare instance of seed migration to the coronary artery through an existing right-to-left cardiac shunt or patent foramen ovale has also been reported. I present a case of seed implant relocation to the heart and left hepatic lobe by way of presumed different venous pathways represented by the periprostatic and hemorrhoidal venous plexuses, respectively.