Venktesh R. Ramnath, MD a, b, Dean R. Hess, PhD, RRT c, d, B. Taylor Thompson, MD b, e, ⁎ 
a Pulmonary and Critical Care Unit, Department of Medicine, Bulfinch 148, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
b Department of Medicine, Harvard Medical School, 55 Shattuck Street, Boston, MA 02115, USA
c Department of Respiratory Care, Ellison 401, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
d Department of Anesthesia, Harvard Medical School, 55 Shattuck Street, Boston, MA 02115, USA
e Medical Intensive Care Unit, Pulmonary and Critical Care Unit, Department of Medicine, Bulfinch 148, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA