Cervical collagen concentration within 15 months after delivery - 19/08/11
Résumé |
Objective |
Cervical collagen concentration decreases during pregnancy. The increased risk of preterm birth after a short interpregnancy interval may be explained by an incomplete remodeling of the cervix. The objective of this study was to describe the changes in cervical collagen concentration over 15 months after delivery.
Study Design |
The collagen concentrations were determined in cervical biopsy specimens that were obtained from 15 women at 3, 6, 9, 12, and 15 months after delivery.
Results |
The mean cervical collagen concentrations were 50%, 59%, 63%, 65%, and 65% of dry weight (SD, 4.2–6.5). This increase was statistically significant until month 9, but not between months 9 and 12.
Conclusion |
Low collagen concentrations in the uterine cervix may contribute to the association between a short interpregnancy interval and preterm birth.
Le texte complet de cet article est disponible en PDF.Key words : cervix, collagen, hydroxyproline, interpregnancy interval, preterm birth
Plan
| Reprints not available from the authors. |
|
| Supported by the Danish Agency for Science Technology and Innovation, the Aarhus University Research Foundation, an Organon Gynecological Research Grant, and the Hede Nielsen Foundation. |
|
| Cite this article as: Sundtoft I, Sommer S, Uldbjerg N. Cervical collagen concentration within 15 months after delivery. Am J Obstet Gynecol 2011;205:59.e1-3. |
Vol 205 - N° 1
P. 59.e1-59.e3 - juillet 2011 Retour au numéro
Article précédent
- Tissue Doppler echocardiographic markers of cardiac dysfunction in small-for-gestational age fetuses
- Montse Comas, Fatima Crispi, Rogelio Cruz-Martinez, Francesc Figueras, Eduard Gratacos
- Maternal serum folate species in early pregnancy and lower genital tract inflammatory milieu
- Hyagriv N. Simhan, Katherine P. Himes, Raman Venkataramanan, Lisa M. Bodnar
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?