Tissue Doppler echocardiographic markers of cardiac dysfunction in small-for-gestational age fetuses - 19/08/11
Reprints: Eduard Gratacós, PhD, Department of Maternal-Fetal Medicine (ICGON), Hospital Clínic, Sabino de Arana 1, 08028, Barcelona, SpainRésumé |
Objective |
The objective of the study was to evaluate echocardiographic markers of cardiac dysfunction in small-for-gestational age (SGA) fetuses with normal umbilical artery Doppler.
Study Design |
Cardiac function was evaluated in 58 SGA (mean gestational age, 38 weeks) and 58 gestational-age matched normally grown fetuses by conventional echocardiography (peak early [E] and late [A] ratios and myocardial performance index [MPI]), and tissue Doppler imaging (TDI) (annular peak velocities and MPI').
Results |
With conventional echocardiography, SGA fetuses had a nonsignificant trend to increased E/A ratios and left MPI compared with controls. TDI demonstrated that SGA fetuses had significantly lower right E' and A' peak velocities and higher MPI' values.
Conclusion |
These findings further support that a proportion of SGA fetuses have true late-onset intrauterine growth restriction, which is associated with subclinical cardiac dysfunction, as previously described for early-onset intrauterine growth restriction.
Le texte complet de cet article est disponible en PDF.Key words : fetal cardiac function, fetal echocardiography, late-onset intrauterine growth restriction, myocardial performance index, small for gestational age, tissue Doppler imaging
Plan
| This study was supported in part by grants from the Fondo de Investigación Sanitaria (PI/060347) (Spain), Centro para el Desarrollo Técnico Industrial (Grant CENIT 20092012, apoyado por el Ministerio de Ciencia e Innovación; y Fondo de Inversión Local Para el Empleo, Spain); Cerebra Foundation for the Brain Injured Child (Carmarthen, UK); and Thrasher Research Fund (Salt Lake City, UT). M.C. was supported by an Emili Letang research grant from the Hospital Clínic; F.C. was supported by a Rio Hortega research grant (CM07/00076) from the Carlos III Institute of Health (Spain); and R.C.-M. was supported by a Marie Curie Host Fellowship for Early Stage Researchers (MEST-CT-2005-19707/FETALMED). |
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| Cite this article as: Comas M, Crispi F, Cruz-Martinez R, et al. Tissue Doppler echocardiographic markers of cardiac dysfunction in small-for-gestational age fetuses. Am J Obstet Gynecol 2011;205:57.e1-6. |
Vol 205 - N° 1
P. 57.e1-57.e6 - juillet 2011 Retour au numéro
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