Comparison of Dynamic Contour Tonometry and Goldmann Applanation Tonometry in Glaucoma Patients and Healthy Subjects - 18/08/11
Inquiries to Franz H. Grus, MD, PhD, Department of Ophthalmology, University of Mainz, 55101 Mainz, GermanyRésumé |
Purpose |
To investigate the agreement in the measurement of intraocular pressure (IOP) obtained by dynamic contour tonometry PASCAL (DCT-PASCAL) and Goldmann applanation tonometry (GAT) in glaucoma eyes and healthy eyes with different central corneal thickness (CCT).
Design |
Prospective cross-sectional study.
Methods |
In a randomized order, three consecutive IOP measurements were performed on 197 eyes of 107 subjects by one examiner using both DCT-PASCAL and GAT on all eyes. Furthermore, ultrasonic pachymetry was performed. The Spearman correlation coefficient (r) was determined to compare IOP readings between DCT-PASCAL and GAT. Regression-based Bland and Altman analysis was used to evaluate agreement between the instruments.
Results |
Mean IOP values obtained by both instruments were significantly correlated in healthy and glaucoma eyes (all healthy eyes [n = 66]: r = 0.8, P < .001, all glaucoma eyes [n = 131]: r = 0.96, P < .001). Neither GAT nor DCT-PASCAL showed a significant correlation with CCT (GAT: all eyes: r = 0.009, P = .9, DCT-PASCAL: all eyes: r = −0.05, P = .5). Bland and Altman analysis revealed the existence of proportional bias. Thus, 95% limits of agreement between the instruments varied with the actual IOP measurement.
Conclusions |
DCT-PASCAL and GAT revealed a strong correlation in IOP measurements between glaucoma and healthy eyes. However, the analysis of agreement indicated some discrepancies between the instruments. Measurements with both GAT and DCT-PASCAL were not correlated with central corneal thickness.
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| Drs Grus and Hoffmann have received research support (instrument) from Swiss Microtechnology AG, Ziemer Ophthalmic Systems Group Company, Switzerland. |
Vol 142 - N° 4
P. 583-590 - octobre 2006 Retour au numéro
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