Evaluation of Lens Epithelial Cell Migration In Vivo at the Haptic-Optic Junction of a One-Piece Hydrophobic Acrylic Intraocular Lens - 18/08/11
Inquiries to Don R. Nixon, MD, Trimed Eye Center, 190 Cundles Road East, Suite 303, Barrie, Ontario, Canada L4M 4S5Résumé |
Purpose |
To evaluate the pattern of lens epithelial cell (LEC) ingrowth behind the intraocular lens (IOL) optic in patients implanted with the AcrySof SA60AT one-piece IOL.
Design |
Retrospective case series.
Methods |
Patients implanted with the AcrySof SA60AT one-piece IOL with complete overlap of the capsulorrhexis and IOL optic and no ocular pathology were selected from the practices of six surgeons. High-resolution digital images of the distribution of LECs were captured. Circumferential location and extent of LEC growth behind the optic were measured.
Results |
Mean ± SD follow-up was 13.2 ± 1.7 months for 40 patients (mean age 72 years). LEC migration beyond the edge of the IOL optic was displayed by 57.5% (23/40) of patients. LECs migrated into the visual axis in 22.5% (9/40) of patients, leading to a visual acuity of <6/9 (20/30) in 10% (4/40) of patients. Cell migration was located preferentially at the optic-haptic junction. Serial photographs were used to monitor LEC migration over time. In some cases, LECs extended from the opposing optic-haptic junctions to converge in the center of the IOL, creating a path across the optic.
Conclusions |
The optic-haptic junction of the AcrySof one-piece IOL is a point of weakness in the barrier effect of the square-edge IOL design that provides migrating LECs access to the posterior capsule.
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| Supported in part by an unrestricted grant from Advanced Medical Optics Inc. |
Vol 142 - N° 4
P. 557-562 - octobre 2006 Retour au numéro
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